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DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia

5-year survival rate for childhood acute lymphoblastic leukemia (ALL) has risen to approximately 90%, yet the causal disease pathway is still poorly understood. Evidence suggests multiple ‘hits’ are required for disease progression; an initial genetic abnormality followed by additional secondary ‘hi...

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Detalhes bibliográficos
Publicado no:Epigenomics
Main Authors: Timms, Jessica A, Relton, Caroline L, Rankin, Judith, Strathdee, Gordon, McKay, Jill A
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928498/
https://ncbi.nlm.nih.gov/pubmed/27035209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2015-0011
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