Clinical Significance of Aberrant DNA Methylation in Childhood Acute Lymphoblastic Leukemia

Methylation profile was analyzed in ninety-five patients with childhood acute lymphoblastic leukemia (ALL). Methylation of both MGMT and p16 genes were associated with higher age (p=0.01 and p=0.03, respectively). Methylation of both p15 and SHP1 genes occurred more frequently in T-ALL than in precu...

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Главные авторы: Takeuchi, Seisho, Matsushita, Masahide, Zimmermann, Martin, Ikezoe, Takayuki, Komatsu, Naoki, Seriu, Taku, Schrappe, Martin, Bartram, Claus R., Koeffler, H. Phillip
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258450/
https://ncbi.nlm.nih.gov/pubmed/21592569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.04.015
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