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Combination therapy in cancer: effects of angiogenesis inhibitors on drug pharmacokinetics and pharmacodynamics

Validated preclinical studies have provided evidence that anti-vascular endothelial growth factor (VEGF) compounds enhance the activity of subsequent antitumor therapy, but the mechanism of this potentiation is far from clear. The most widespread explanation is enhanced delivery of therapeutics due...

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Détails bibliographiques
Publié dans:Chin J Cancer
Auteurs principaux: Fuso Nerini, Ilaria, Cesca, Marta, Bizzaro, Francesca, Giavazzi, Raffaella
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928348/
https://ncbi.nlm.nih.gov/pubmed/27357621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0123-1
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