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Combination therapy in cancer: effects of angiogenesis inhibitors on drug pharmacokinetics and pharmacodynamics

Validated preclinical studies have provided evidence that anti-vascular endothelial growth factor (VEGF) compounds enhance the activity of subsequent antitumor therapy, but the mechanism of this potentiation is far from clear. The most widespread explanation is enhanced delivery of therapeutics due...

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Detalhes bibliográficos
Publicado no:Chin J Cancer
Main Authors: Fuso Nerini, Ilaria, Cesca, Marta, Bizzaro, Francesca, Giavazzi, Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928348/
https://ncbi.nlm.nih.gov/pubmed/27357621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0123-1
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