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Combination therapy in cancer: effects of angiogenesis inhibitors on drug pharmacokinetics and pharmacodynamics

Validated preclinical studies have provided evidence that anti-vascular endothelial growth factor (VEGF) compounds enhance the activity of subsequent antitumor therapy, but the mechanism of this potentiation is far from clear. The most widespread explanation is enhanced delivery of therapeutics due...

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Bibliografiske detaljer
Udgivet i:Chin J Cancer
Main Authors: Fuso Nerini, Ilaria, Cesca, Marta, Bizzaro, Francesca, Giavazzi, Raffaella
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928348/
https://ncbi.nlm.nih.gov/pubmed/27357621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0123-1
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