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Large scale analysis of protein stability in OMIM disease related human protein variants
BACKGROUND: Modern genomic techniques allow to associate several Mendelian human diseases to single residue variations in different proteins. Molecular mechanisms explaining the relationship among genotype and phenotype are still under debate. Change of protein stability upon variation appears to as...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Genomics |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4928156/ https://ncbi.nlm.nih.gov/pubmed/27356511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2726-y |
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