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Large scale analysis of protein stability in OMIM disease related human protein variants
BACKGROUND: Modern genomic techniques allow to associate several Mendelian human diseases to single residue variations in different proteins. Molecular mechanisms explaining the relationship among genotype and phenotype are still under debate. Change of protein stability upon variation appears to as...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4928156/ https://ncbi.nlm.nih.gov/pubmed/27356511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2726-y |
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