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A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice

DNA vaccines are cost-effective to manufacture on a global scale and Tat-based DNA vaccines have yielded protective outcomes in preclinical and clinical models of human immunodeficiency virus (HIV), highlighting the potential of such vaccines. However, Tat-based DNA vaccines have been poorly immunog...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tomusange, Khamis, Wijesundara, Danushka, Gummow, Jason, Garrod, Tamsin, Li, Yanrui, Gray, Lachlan, Churchill, Melissa, Grubor-Bauk, Branka, Gowans, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928126/
https://ncbi.nlm.nih.gov/pubmed/27358023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29131
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