A Multiantigenic DNA Vaccine That Induces Broad Hepatitis C Virus-Specific T-Cell Responses in Mice

There are 3 to 4 million new hepatitis C virus (HCV) infections annually around the world, but no vaccine is available. Robust T-cell mediated responses are necessary for effective clearance of the virus, and DNA vaccines result in a cell-mediated bias. Adjuvants are often required for effective vac...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Gummow, Jason, Li, Yanrui, Yu, Wenbo, Garrod, Tamsin, Wijesundara, Danushka, Brennan, Amelia J., Mullick, Ranajoy, Voskoboinik, Ilia, Grubor-Bauk, Branka, Gowans, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505674/
https://ncbi.nlm.nih.gov/pubmed/26018154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00803-15
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