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Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials

Translation of novel therapies from bench to bedside is hampered by profound disparities between animal and human genetics and physiology. The ability to test for efficacy and cardiotoxicity in a clinically relevant human model system would enable more rapid therapy development. We have developed a...

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Foilsithe in:Sci Rep
Main Authors: Kang, C., Qiao, Y., Li, G., Baechle, K., Camelliti, P., Rentschler, S., Efimov, I. R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928074/
https://ncbi.nlm.nih.gov/pubmed/27356882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28798
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