Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies.
V(D)J [variable-(diversity)-joining] rearrangements occur between, as well as within, immune receptor loci, resulting in the generation of hybrid antigen-receptor genes and the formation of a variety of lymphocyte-specific chromosomal aberrations. Such hybrid genes occur at a low frequency in the pe...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1608939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5301 |
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