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Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies.

V(D)J [variable-(diversity)-joining] rearrangements occur between, as well as within, immune receptor loci, resulting in the generation of hybrid antigen-receptor genes and the formation of a variety of lymphocyte-specific chromosomal aberrations. Such hybrid genes occur at a low frequency in the pe...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lipkowitz, S, Garry, V F, Kirsch, I R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1608939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5301
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