Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event.

A series of bicyclams have been shown to be potent and selective inhibitors of human immunodeficiency virus (HIV). The compounds are inhibitory to the replication of various HIV-1 and HIV-2 strains in various human T-cell systems, including peripheral blood lymphocytes, at 0.14-1.4 microM, without b...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: De Clercq, E, Yamamoto, N, Pauwels, R, Baba, M, Schols, D, Nakashima, H, Balzarini, J, Debyser, Z, Murrer, B A, Schwartz, D
Formato: Artigo
Idioma:Inglês
Publicado: 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC49276/
https://ncbi.nlm.nih.gov/pubmed/1608936
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares