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Bicyclams, Selective Antagonists of the Human Chemokine Receptor CXCR4, Potently Inhibit Feline Immunodeficiency Virus Replication

Bicyclams are low-molecular-weight anti-human immunodeficiency virus (HIV) agents that have been shown to act as potent and selective CXC chemokine receptor 4 (CXCR4) antagonists. Here, we demonstrate that bicyclams are potent inhibitors of feline immunodeficiency virus (FIV) replication when evalua...

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Auteurs principaux: Egberink, Herman F., De Clercq, Erik, Van Vliet, Arno L. W., Balzarini, Jan, Bridger, Gary J., Henson, Geoffrey, Horzinek, Marian C., Schols, Dominique
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112713/
https://ncbi.nlm.nih.gov/pubmed/10400726
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