Efficacy of Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis: an open-label dose-ranging study

BACKGROUND: Cryptococcus is the most common cause of adult meningitis in Africa. We evaluated the activity of adjunctive sertraline, previously demonstrated to have in vitro and in vivo activity against Cryptococcus. METHODS: We enrolled 172 HIV-infected Ugandans with cryptococcal meningitis from Au...

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Detalhes bibliográficos
Publicado no:Lancet Infect Dis
Main Authors: Rhein, Joshua, Morawski, Bozena M, Hullsiek, Kathy Huppler, Nabeta, Henry W, Kiggundu, Reuben, Tugume, Lillian, Musubire, Abdu, Akampurira, Andrew, Smith, Kyle D, Alhadab, Ali, Williams, Darlisha A, Abassi, Mahsa, Bahr, Nathan C, Velamakanni, Sruti S, Fisher, James, Nielsen, Kirsten, Meya, David B, Boulware, David R
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927382/
https://ncbi.nlm.nih.gov/pubmed/26971081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(16)00074-8
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