Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity

Intermediate progenitors (IPs) amplify production of pyramidal neurons, but their role in selective genesis of cortical layers or neuronal subtypes remains unclear. Using genetic lineage tracing in mice, we find that IPs destined to produce upper cortical layers first appear early in corticogenesis,...

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Publié dans:Cell Rep
Auteurs principaux: Mihalas, Anca B., Elsen, Gina E., Bedogni, Francesco, Daza, Ray A. M., Ramos-Laguna, Kevyn A., Arnold, Sebastian J., Hevner, Robert F.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927342/
https://ncbi.nlm.nih.gov/pubmed/27320921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.072
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