Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity

Intermediate progenitors (IPs) amplify production of pyramidal neurons, but their role in selective genesis of cortical layers or neuronal subtypes remains unclear. Using genetic lineage tracing in mice, we find that IPs destined to produce upper cortical layers first appear early in corticogenesis,...

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Vydáno v:Cell Rep
Hlavní autoři: Mihalas, Anca B., Elsen, Gina E., Bedogni, Francesco, Daza, Ray A. M., Ramos-Laguna, Kevyn A., Arnold, Sebastian J., Hevner, Robert F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927342/
https://ncbi.nlm.nih.gov/pubmed/27320921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.072
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