INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

Superenhancers (SEs) are large genomic regions with a high density of enhancer marks. In cancer, SEs are found near oncogenes and dictate cancer gene expression. However, how oncogenic SEs are regulated remains poorly understood. Here, we show that INO80, a chromatin remodeling complex, is required...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Zhou, Bingying, Wang, Li, Zhang, Shu, Bennett, Brian D., He, Fan, Zhang, Yan, Xiong, Chengliang, Han, Leng, Diao, Lixia, Li, Pishun, Fargo, David C., Cox, Adrienne D., Hu, Guang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926866/
https://ncbi.nlm.nih.gov/pubmed/27340176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277178.115
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