INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

Superenhancers (SEs) are large genomic regions with a high density of enhancer marks. In cancer, SEs are found near oncogenes and dictate cancer gene expression. However, how oncogenic SEs are regulated remains poorly understood. Here, we show that INO80, a chromatin remodeling complex, is required...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Zhou, Bingying, Wang, Li, Zhang, Shu, Bennett, Brian D., He, Fan, Zhang, Yan, Xiong, Chengliang, Han, Leng, Diao, Lixia, Li, Pishun, Fargo, David C., Cox, Adrienne D., Hu, Guang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926866/
https://ncbi.nlm.nih.gov/pubmed/27340176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277178.115
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia