Involvement of the Striatal Medium Spiny Neurons of the Direct Pathway in the Motor Stimulant Effects of Phencyclidine

BACKGROUND: The psychotomimetic phencyclidine (PCP) produces behavioral symptoms similar to those observed in schizophrenia, accompanied by increased motor activity. The dopamine and adenosine 3’,5’-cyclic monophosphate-regulated phosphoprotein of 32kDa (DARPP-32) is enriched in the medium spiny neu...

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Bibliographic Details
Published in:Int J Neuropsychopharmacol
Main Authors: Bonito-Oliva, Alessandra, DuPont, Caitlin, Madjid, Nather, Ögren, Sven Ove, Fisone, Gilberto
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926795/
https://ncbi.nlm.nih.gov/pubmed/26657176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv134
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