Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advantage of Dual versus Single Drug Approaches

BACKGROUND: Despite its success in treating specific anxiety disorders, the effect of exposure therapy is limited by problems with tolerability, treatment resistance, and fear relapse after initial response. The identification of novel drug targets facilitating fear extinction in clinically relevant...

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Publicado en:Int J Neuropsychopharmacol
Main Authors: Sartori, Simone B., Maurer, Verena, Murphy, Conor, Schmuckermair, Claudia, Muigg, Patrick, Neumann, Inga D., Whittle, Nigel, Singewald, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926792/
https://ncbi.nlm.nih.gov/pubmed/26625894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv128
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