Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advantage of Dual versus Single Drug Approaches

BACKGROUND: Despite its success in treating specific anxiety disorders, the effect of exposure therapy is limited by problems with tolerability, treatment resistance, and fear relapse after initial response. The identification of novel drug targets facilitating fear extinction in clinically relevant...

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Publicat a:Int J Neuropsychopharmacol
Autors principals: Sartori, Simone B., Maurer, Verena, Murphy, Conor, Schmuckermair, Claudia, Muigg, Patrick, Neumann, Inga D., Whittle, Nigel, Singewald, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926792/
https://ncbi.nlm.nih.gov/pubmed/26625894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv128
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