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IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples

Objective Currently, there is a disconnect between finding a patient’s relevant molecular profile and predicting actionable therapeutics. Here we develop and implement the Integrating Molecular Profiles with Actionable Therapeutics (IMPACT) analysis pipeline, linking variants detected from whole-exo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Med Inform Assoc
Prif Awduron: Hintzsche, Jennifer, Kim, Jihye, Yadav, Vinod, Amato, Carol, Robinson, Steven E, Seelenfreund, Eric, Shellman, Yiqun, Wisell, Joshua, Applegate, Allison, McCarter, Martin, Box, Neil, Tentler, John, De, Subhajyoti, Robinson, William A, Tan, Aik Choon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926746/
https://ncbi.nlm.nih.gov/pubmed/27026619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocw022
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