Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease

Many somatic mutations have been detected in pancreatic ductal adenocarcinoma (PDAC), leading to the identification of some key drivers of disease progression, but the involvement of large genomic rearrangements has often been overlooked. In this study, we performed mate pair sequencing (MPseq) on g...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Murphy, Stephen J., Hart, Steven N., Halling, Geoffrey C., Johnson, Sarah H., Smadbeck, James B., Drucker, Travis, Lima, Joema Felipe, Rohakhtar, Fariborz Rakhshan, Harris, Faye R., Kosari, Farhad, Subramanian, Subbaya, Petersen, Gloria M., Wiltshire, Timothy D., Kipp, Benjamin R., Truty, Mark J., McWilliams, Robert R., Couch, Fergus J., Vasmatzis, George
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926317/
https://ncbi.nlm.nih.gov/pubmed/26676757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2198
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