Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease

Many somatic mutations have been detected in pancreatic ductal adenocarcinoma (PDAC), leading to the identification of some key drivers of disease progression, but the involvement of large genomic rearrangements has often been overlooked. In this study, we performed mate pair sequencing (MPseq) on g...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Murphy, Stephen J., Hart, Steven N., Halling, Geoffrey C., Johnson, Sarah H., Smadbeck, James B., Drucker, Travis, Lima, Joema Felipe, Rohakhtar, Fariborz Rakhshan, Harris, Faye R., Kosari, Farhad, Subramanian, Subbaya, Petersen, Gloria M., Wiltshire, Timothy D., Kipp, Benjamin R., Truty, Mark J., McWilliams, Robert R., Couch, Fergus J., Vasmatzis, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926317/
https://ncbi.nlm.nih.gov/pubmed/26676757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2198
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