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Extrinsic allospecific signals of hematopoietic origin dictate iNKT cell lineage-fate decisions during development

Invariant NKT (iNKT) cells are critical to the maintenance of tolerance toward alloantigens encountered during postnatal life pointing to the existence of a process for self-education. However, the impact of developmentally encountered alloantigens in shaping the phenotype and function of iNKT cells...

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Publicat a:Sci Rep
Autors principals: Strong, Beverly S. I., Newkold, Tess J., Lee, Amanda E., Turner, Lucas E., Alhajjat, Amir M., Heusel, Jonathan W., Shaaban, Aimen F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926280/
https://ncbi.nlm.nih.gov/pubmed/27354027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28837
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