Synthesis of Phthalimide Derivatives as Potential PPAR-γ Ligands

Paecilocin A, a phthalide derivative isolated from the jellyfish-derived fungus Paecilomyces variotii, activates PPAR-γ (Peroxisome proliferator-activated receptor gamma) in rat liver Ac2F cells. Based on a SAR (Structure-activity relationships) study and in silico analysis of paecilocin A-mimetic d...

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Vydáno v:Mar Drugs
Hlavní autoři: Eom, So Hyeon, Liu, Sen, Su, Mingzhi, Noh, Tae Hwan, Hong, Jongki, Kim, Nam Deuk, Chung, Hae Young, Yang, Min Hye, Jung, Jee H.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926071/
https://ncbi.nlm.nih.gov/pubmed/27338418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14060112
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