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Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)

IFI16 and AIM2 are important DNA sensors in antiviral immunity. To characterize these two molecules in a woodchuck model, which is widely used to study hepatitis B virus (HBV) infection, we cloned and analyzed the complete coding sequences (CDSs) of woodchuck IFI16 and AIM2, and found that AIM2 was...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yan, Qi, Li, Mengmeng, Liu, Qin, Li, Fanghui, Zhu, Bin, Wang, Junzhong, Lu, Yinping, Liu, Jia, Wu, Jun, Zheng, Xin, Lu, Mengji, Wang, Baoju, Yang, Dongliang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926060/
https://ncbi.nlm.nih.gov/pubmed/27354260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28776
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