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Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Lau, Ho-Tak, Liu, Lizhi, Li, Xiajun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926020/
https://ncbi.nlm.nih.gov/pubmed/27345984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.12.038
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