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Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

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Detalles Bibliográficos
Publicado en:Stem Cell Res
Autores principales: Lau, Ho-Tak, Liu, Lizhi, Li, Xiajun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926020/
https://ncbi.nlm.nih.gov/pubmed/27345984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.12.038
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