Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells()

Despite the tremendous advances in the treatment of childhood solid tumors, rhabdomyosarcoma (RMS) continues to provide a therapeutic challenge. Children with metastatic or relapsed disease have a disease-free survival rate under 30%. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that...

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Bibliografske podrobnosti
izdano v:Transl Oncol
Main Authors: Waters, Alicia M., Stafman, Laura L., Garner, Evan F., Mruthyunjayappa, Smitha, Stewart, Jerry E., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2016
Teme:
Original article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925808/
https://ncbi.nlm.nih.gov/pubmed/27567948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2016.06.001
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