A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

There is growing evidence of shared risk alleles between complex traits (pleiotropy), including autoimmune and neuropsychiatric diseases. This might be due to sharing between all individuals (whole-group pleiotropy), or a subset of individuals within a genetically heterogeneous cohort (subgroup hete...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Han, Buhm, Pouget, Jennie G., Slowikowski, Kamil, Stahl, Eli, Lee, Cue Hyunkyu, Diogo, Dorothee, Hu, Xinli, Park, Yu Rang, Kim, Eunji, Gregersen, Peter K., Dahlqvist, Solbritt Rantapää, Worthington, Jane, Martin, Javier, Eyre, Steve, Klareskog, Lars, Huizinga, Tom, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S., Wray, Naomi R., Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925284/
https://ncbi.nlm.nih.gov/pubmed/27182969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3572
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados