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Toward the Synthesis of Nuphar Sesquiterpene Thioalkaloids: Stereodivergent Rhodium-Catalyzed Synthesis of the Thiolane Subunit

A stereodivergent approach to the central thiolane subunit of Nuphar sesquiterpene thioalkaloids has been developed. This approach features a rhodium-catalyzed Stevens-type rearrangement in conjunction with an enzyme resolution reaction. Further elaboration into a polycyclic ring system via alcohol...

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Publicado en:J Org Chem
Main Authors: Lu, Ping, Herrmann, Aaron T., Zakarian, Armen
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924923/
https://ncbi.nlm.nih.gov/pubmed/26147579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b01177
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