Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

Meningiomas are frequent central nervous system tumors. Although most meningiomas are benign (WHO grade I) and curable by surgery, WHO grade II and III tumors remain therapeutically challenging due to frequent recurrence. Interestingly, relapse also occurs in some WHO grade I meningiomas. Hence, we...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schmidt, Melissa, Mock, Andreas, Jungk, Christine, Sahm, Felix, Ull, Anna Theresa, Warta, Rolf, Lamszus, Katrin, Gousias, Konstantinos, Ketter, Ralf, Roesch, Saskia, Rapp, Carmen, Schefzyk, Sebastian, Urbschat, Steffi, Lahrmann, Bernd, Kessler, Almuth F., Löhr, Mario, Senft, Christian, Grabe, Niels, Reuss, David, Beckhove, Philipp, Westphal, Manfred, von Deimling, Andreas, Unterberg, Andreas, Simon, Matthias, Herold-Mende, Christel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924735/
https://ncbi.nlm.nih.gov/pubmed/26894859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7396
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