Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone

BACKGROUND: The spatial relationship of glioblastoma (GBM) to the subventricular zone (SVZ) is associated with inferior patient survival. However, the underlying molecular phenotype is largely unknown. We interrogated an SVZ-dependent transcriptome and potential location-specific prognostic markers....

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Jungk, Christine, Mock, Andreas, Exner, Janina, Geisenberger, Christoph, Warta, Rolf, Capper, David, Abdollahi, Amir, Friauf, Sara, Lahrmann, Bernd, Grabe, Niels, Beckhove, Philipp, von Deimling, Andreas, Unterberg, Andreas, Herold-Mende, Christel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080721/
https://ncbi.nlm.nih.gov/pubmed/27782828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-016-0710-7
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