GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression enhances migration, invasion, and metastasis of cancer cells. SPDEF expressio...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Tamura, Rodrigo E., Paccez, Juliano D., Duncan, Kristal C., Morale, Mirian G., Simabuco, Fernando M., Dillon, Simon, Correa, Ricardo G., Gu, Xuesong, Libermann, Towia A., Zerbini, Luiz F.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924684/
https://ncbi.nlm.nih.gov/pubmed/26885618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7355
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