GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression enhances migration, invasion, and metastasis of cancer cells. SPDEF expressio...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Tamura, Rodrigo E., Paccez, Juliano D., Duncan, Kristal C., Morale, Mirian G., Simabuco, Fernando M., Dillon, Simon, Correa, Ricardo G., Gu, Xuesong, Libermann, Towia A., Zerbini, Luiz F.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924684/
https://ncbi.nlm.nih.gov/pubmed/26885618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7355
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