GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF expression blocks migration and invasion, knockdown of SPDEF expression enhances migration, invasion, and metastasis of cancer cells. SPDEF expressio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tamura, Rodrigo E., Paccez, Juliano D., Duncan, Kristal C., Morale, Mirian G., Simabuco, Fernando M., Dillon, Simon, Correa, Ricardo G., Gu, Xuesong, Libermann, Towia A., Zerbini, Luiz F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924684/
https://ncbi.nlm.nih.gov/pubmed/26885618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7355
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