Effect of HMGCR genetic variation on neuroimaging biomarkers in healthy, mild cognitive impairment and Alzheimer's disease cohorts

Alzheimer's disease (AD) has become a considerable public health issue. The mechanisms underlying AD onset and progression remain largely unclear. 3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is a strong functional AD candidate gene because it encodes part of the statin-binding domai...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cao, Lei, Wang, Hui-Fu, Tan, Lin, Sun, Fu-Rong, Tan, Meng-Shan, Tan, Chen-Chen, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924644/
https://ncbi.nlm.nih.gov/pubmed/26950278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7797
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