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Quantification and Classification of E. coli Proteome Utilization and Unused Protein Costs across Environments

The costs and benefits of protein expression are balanced through evolution. Expression of un-utilized protein (that have no benefits in the current environment) incurs a quantifiable fitness costs on cellular growth rates; however, the magnitude and variability of un-utilized protein expression in...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: O’Brien, Edward J., Utrilla, Jose, Palsson, Bernhard O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924638/
https://ncbi.nlm.nih.gov/pubmed/27351952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004998
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