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DNA-PK Deficiency in Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by neuronal death with an accumulaton of intra-cellular neurofibrillary tangles (NFT) and extracellular amyloid plaques. Reduced DNA repair ability has been reported in AD brains. In neurons, the predominant mechanism to repair double-strand DNA breaks (DSB)...
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| Publicado no: | J Neurol Neuromedicine |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924576/ https://ncbi.nlm.nih.gov/pubmed/27376156 |
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