Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

Thermosensitive Transient Receptor Potential (TRP) channels are believed to respond to either cold or heat. In the case of TRP subtype A1 (TRPA1), there seems to be a species-dependent divergence in temperature sensation as non-mammalian TRPA1 is heat-sensitive whereas mammalian TRPA1 is sensitive t...

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Publicado en:Sci Rep
Main Authors: Moparthi, Lavanya, Kichko, Tatjana I., Eberhardt, Mirjam, Högestätt, Edward D., Kjellbom, Per, Johanson, Urban, Reeh, Peter W., Leffler, Andreas, Filipovic, Milos R., Zygmunt, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923899/
https://ncbi.nlm.nih.gov/pubmed/27349477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28763
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