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Potential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin

The transient precorneal retention time and low penetration capacity into intraocular tissues are the key obstacles that hinder the ophthalmic drug delivery of many therapeutic compounds, especially for drugs with poor solubility and permeability. To break the stalemate, N-acetyl-L-cysteine function...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Liu, Dandan, Li, Jinyu, Pan, Hao, He, Fengwei, Liu, Zhidong, Wu, Qingyin, Bai, Chunping, Yu, Shihui, Yang, Xinggang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923878/
https://ncbi.nlm.nih.gov/pubmed/27350323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28796
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