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Potential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin

The transient precorneal retention time and low penetration capacity into intraocular tissues are the key obstacles that hinder the ophthalmic drug delivery of many therapeutic compounds, especially for drugs with poor solubility and permeability. To break the stalemate, N-acetyl-L-cysteine function...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Dandan, Li, Jinyu, Pan, Hao, He, Fengwei, Liu, Zhidong, Wu, Qingyin, Bai, Chunping, Yu, Shihui, Yang, Xinggang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923878/
https://ncbi.nlm.nih.gov/pubmed/27350323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28796
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