Altering the Substrate Specificity of Organophosphorus Hydrolase for Enhanced Hydrolysis of Chlorpyrifos

Chlorpyrifos is one of the most popular pesticides used for agriculture crop protection, and widespread contamination is a potential concern. However, chlorpyrifos is hydrolyzed almost 1,000-fold slower than the preferred substrate, paraoxon, by organophosphorus hydrolase (OPH), an enzyme that can d...

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Pubblicato in:	Appl Environ Microbiol
Autori principali:	Cho, Catherine Mee-Hie, Mulchandani, Ashok, Chen, Wilfred
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Physiology and Biotechnology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC492387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15294802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.8.4681-4685.2004
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