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Chimpanzees immunized with recombinant soluble CD4 develop anti-self CD4 antibody responses with anti-human immunodeficiency virus activity.

In view of the efficiency with which human immunodeficiency virus replication can be blocked in vitro with anti-CD4 antibodies, the elicitation of an anti-CD4 antibody response through active immunization might represent a useful therapeutic strategy for AIDS. Here we demonstrate that immunization o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Watanabe, M, Boyson, J E, Lord, C I, Letvin, N L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49237/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.5103
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