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Chimpanzees immunized with recombinant soluble CD4 develop anti-self CD4 antibody responses with anti-human immunodeficiency virus activity.

In view of the efficiency with which human immunodeficiency virus replication can be blocked in vitro with anti-CD4 antibodies, the elicitation of an anti-CD4 antibody response through active immunization might represent a useful therapeutic strategy for AIDS. Here we demonstrate that immunization o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Watanabe, M, Boyson, J E, Lord, C I, Letvin, N L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49237/
https://ncbi.nlm.nih.gov/pubmed/1594618
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