Bone marrow fibrosis in primary myelofibrosis: pathogenic mechanisms and the role of TGF-β

Primary myelofibrosis (PMF) is a Philadelphia chromosome negative myeloproliferative neoplasm (MPN) with adverse prognosis and is associated with bone marrow fibrosis and extramedullary hematopoiesis. Even though the discovery of the Janus kinase 2 (JAK2), thrombopoietin receptor (MPL) and calreticu...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cell Investig
Autori principali: Agarwal, Archana, Morrone, Kerry, Bartenstein, Matthias, Zhao, Zhizhuang Joe, Verma, Amit, Goel, Swati
Natura: Artigo
Lingua:Inglês
Pubblicazione: AME Publishing Company 2016
Soggetti:
Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923632/
https://ncbi.nlm.nih.gov/pubmed/27358897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2306-9759.2016.02.03
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