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Bone marrow fibrosis in primary myelofibrosis: pathogenic mechanisms and the role of TGF-β
Primary myelofibrosis (PMF) is a Philadelphia chromosome negative myeloproliferative neoplasm (MPN) with adverse prognosis and is associated with bone marrow fibrosis and extramedullary hematopoiesis. Even though the discovery of the Janus kinase 2 (JAK2), thrombopoietin receptor (MPL) and calreticu...
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| Publicado no: | Stem Cell Investig |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4923632/ https://ncbi.nlm.nih.gov/pubmed/27358897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2306-9759.2016.02.03 |
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