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TGF-β1 induces bone marrow reticulin fibrosis in hairy cell leukemia

The mechanisms that lead to reticulin fibrosis of bone marrow (BM) in hairy cell leukemia (HCL) are not fully understood. We therefore investigated the involvement of TGF-β1, a potent fibrogenic cytokine, in this process. Immunoassays revealed that TGF-β1 is present at higher concentrations in BM, s...

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Detalhes bibliográficos
Main Authors: Shehata, Medhat, Schwarzmeier, Josef D., Hilgarth, Martin, Hubmann, Rainer, Duechler, Markus, Gisslinger, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC351317/
https://ncbi.nlm.nih.gov/pubmed/14991065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419540
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