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TGF-β1 induces bone marrow reticulin fibrosis in hairy cell leukemia

The mechanisms that lead to reticulin fibrosis of bone marrow (BM) in hairy cell leukemia (HCL) are not fully understood. We therefore investigated the involvement of TGF-β1, a potent fibrogenic cytokine, in this process. Immunoassays revealed that TGF-β1 is present at higher concentrations in BM, s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shehata, Medhat, Schwarzmeier, Josef D., Hilgarth, Martin, Hubmann, Rainer, Duechler, Markus, Gisslinger, Heinz
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC351317/
https://ncbi.nlm.nih.gov/pubmed/14991065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419540
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