Metallothioneins 1 and 2 Modulate Inflammation and Support Remodeling in Ischemic Cardiomyopathy in Mice

Aims. Repetitive brief ischemia and reperfusion (I/R) is associated with left ventricular dysfunction during development of ischemic cardiomyopathy. We investigated the role of zinc-donor proteins metallothionein MT1 and MT2 in a closed-chest murine model of I/R. Methods. Daily 15-minute LAD-occlusi...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Duerr, Georg D., Dewald, Daniela, Schmitz, Eva J., Verfuerth, Luise, Keppel, Katharina, Peigney, Christine, Ghanem, Alexander, Welz, Armin, Dewald, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923606/
https://ncbi.nlm.nih.gov/pubmed/27403038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7174127
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