Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species

We examined the effects of daily repetitive brief (15 min) myocardial ischemia and reperfusion (I/R) in WT C57/BL6 and extracellular superoxide dismutase (EC-SOD)-overexpressing mice. In the absence of myocardial necrosis, I/R resulted in persistent fibrosis in ischemic areas of C57/BL6 mice associa...

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Detalhes bibliográficos
Main Authors: Dewald, Oliver, Frangogiannis, Nikolaos G., Zoerlein, Martin, Duerr, Georg D., Klemm, Christina, Knuefermann, Pascal, Taffet, George, Michael, Lloyd H., Crapo, James D., Welz, Armin, Entman, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151404/
https://ncbi.nlm.nih.gov/pubmed/12586861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0438035100
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