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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation

The adverse biological effects of ionizing radiation (IR) are commonly attributed to the generation of DNA double-strand breaks (DSBs). IR-induced DSBs are generated by clusters of ionizations, bear damaged terminal nucleotides, and frequently comprise base damages and single-strand breaks in the vi...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Mladenova, Veronika, Mladenov, Emil, Iliakis, George
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923065/
https://ncbi.nlm.nih.gov/pubmed/27446809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00163
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